Реакция #9232

Уравнение реакции

1-(6-benzyl-2-benzothiazolyl)-3-ethylurea

2-amino-6-ethoxycarbonyl-benzothiazole

triethylamine

ethyl isocyanate

→

desired compound

Выход 82.0%

1-(6-Ethoxycarbonyl-2-benzothiazolyl)-3-ethylurea

Выход 82.0%

Растворители

toluene

Условия реакции

Обработка

1. 1
   Другоеwas reacted

Методика

According to the General Procedure for 1-(6-substituted-2-benzothiazolyl)-3-ethylurea compounds, and similar to the synthesis of 1-(6-benzyl-2-benzothiazolyl)-3-ethylurea, a mixture of 2-amino-6-ethoxycarbonyl-benzothiazole, triethylamine and ethyl isocyanate in toluene was reacted to give the desired compound 2.40 g (82%). LC/MS 294.0 (M+1); LC retention time 4.29 min.

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