Реакция #91257

Уравнение реакции

3-Chloromethyl-2-isopropylsulfanyl-pyridine

2-(4-hydroxy-2,3-dimethyl-phenyl)-cyclopropane carboxylic acid ethyl ester

→

title compound

Выход 81.3%

2-[4-(2-isopropylsulfanyl-pyridin-3-ylmethoxy)-2,3-dimethyl-phenyl]-cyclopropane carboxylic acid

Выход 81.3%

Условия реакции

Обработка

1. 1
   Другоеto react sequentially in the same manner as in Steps A and B of Example 1

Методика

3-Chloromethyl-2-isopropylsulfanyl-pyridine (0.030 g, 0.149 mmol) obtained in Step C of Preparation Example 1 and 2-(4-hydroxy-2,3-dimethyl-phenyl)-cyclopropane carboxylic acid ethyl ester (0.035 g, 0.149 mmol) obtained in Step C of Preparation Example 48 were used to react sequentially in the same manner as in Steps A and B of Example 1 to obtain the title compound (0.045 g, 81%).

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