Реакция #91242

Уравнение реакции

3-Chloromethyl-2-cyclopentylsulfanyl-pyridine

2-(3-fluoro-4-hydroxy-phenyl)-cyclopropane carboxylic acid ethyl ester

→

title compound

Выход 101.7%

2-[4-(2-cyclopentylsulfanyl-pyridin-3-ylmethoxy)-3-fluoro-phenyl]-cyclopropane carboxylic acid

Выход 101.7%

Условия реакции

Обработка

1. 1
   Другоеto react sequentially in the same manner as in Steps A and B of Example 1

Методика

3-Chloromethyl-2-cyclopentylsulfanyl-pyridine (0.040 g, 0.17 mmol) obtained in Step C of Preparation Example 8 and 2-(3-fluoro-4-hydroxy-phenyl)-cyclopropane carboxylic acid ethyl ester (0.040 g, 0.17 mmol) obtained in Step C of Preparation Example 44 were used to react sequentially in the same manner as in Steps A and B of Example 1 to obtain the title compound (0.067 g, 98%).

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