Реакция #91239

Уравнение реакции

3-Chloromethyl-2-isopropylsulfanyl-pyridine

2-[3-fluoro-4-hydroxy-phenyl]-cyclopropane carboxylic acid ethyl ester

→

title compound

Выход 84.0%

2-[3-fluoro-4-(2-isopropylsulfanyl-pyridin-3-ylmethoxy)-phenyl]-cyclopropane carboxylic acid

Выход 84.0%

Условия реакции

Обработка

1. 1
   Другоеto react sequentially in the same manner as in Steps A and B of Example 1

Методика

3-Chloromethyl-2-isopropylsulfanyl-pyridine (0.040 g, 0.20 mmol) obtained in Step C of Preparation Example 1 and 2-[3-fluoro-4-hydroxy-phenyl]-cyclopropane carboxylic acid ethyl ester (0.044 g, 0.20 mmol) obtained in Step C of Preparation Example 44 were used to react sequentially in the same manner as in Steps A and B of Example 1 to obtain the title compound (0.060 g, 84%).

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