Реакция #90098

ord-d4c4f8f8444e4115aa552beffed17e5a

Уравнение реакции

COc1ccc2c(c1)C(C)(C)C(=O)CC2
Compound A2
COc1ccc2c(c1)C(C)(C)C(=O)CC2
7-Methoxy-1,1-dimethyl-3,4-dihydro-1H-naphthalen-2-one
N#Cc1cc(NN)ccc1F
3-cyano-4-fluorophenylhydrazine
→
COc1ccc2c(c1)C(C)(C)c1[nH]c3cc(C#N)c(F)cc3c1C2
title compound
COc1ccc2c(c1)C(C)(C)c1[nH]c3cc(C#N)c(F)cc3c1C2
2-Fluoro-8-methoxy-6,6-dimethyl-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile

Реактанты

COc1ccc2c(c1)C(C)(C)C(=O)CC2
Compound A2
COc1ccc2c(c1)C(C)(C)C(=O)CC2
7-Methoxy-1,1-dimethyl-3,4-dihydro-1H-naphthalen-2-one
N#Cc1cc(NN)ccc1F
3-cyano-4-fluorophenylhydrazine

Реагенты

Нет

Условия реакции

Подробные условия
See reaction.notes.procedure_details.

Обработка

  1. 1
    ДругоеUnder the same conditions as the method for synthesizing Compound A3-1

Методика

Under the same conditions as the method for synthesizing Compound A3-1, the title compound was prepared from Compound A2 and 3-cyano-4-fluorophenylhydrazine.

Источник

DOI: 10.6084/m9.figshare.5104873.v1Патент: US09440922B2uspto-grants-2016_09