Реакция #89975

ord-dbe85b7018be433488cbb675fdbd2e3f

Уравнение реакции

CC1(C)c2cc(O)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21
Compound A6
CC1(C)c2cc(O)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21
8-Hydroxy-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
OC1CCOCC1
tetrahydropyran-4-ol
→
CC1(C)c2cc(OC3CCOCC3)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21
title compound
CC1(C)c2cc(OC3CCOCC3)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21
6,6-Dimethyl-11-oxo-8-(tetrahydro-pyran-4-yloxy)-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile

Реактанты

CC1(C)c2cc(O)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21
Compound A6
CC1(C)c2cc(O)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21
8-Hydroxy-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
OC1CCOCC1
tetrahydropyran-4-ol

Реагенты

Нет

Условия реакции

Подробные условия
See reaction.notes.procedure_details.

Обработка

  1. 1
    ДругоеUnder the same conditions as the method for synthesizing Compound A7-1

Методика

Under the same conditions as the method for synthesizing Compound A7-1, the title compound was prepared from Compound A6 and tetrahydropyran-4-ol.

Источник

DOI: 10.6084/m9.figshare.5104873.v1Патент: US09440922B2uspto-grants-2016_09