Реакция #85034

Уравнение реакции

tert-butyl 2-[4-(5-chloro-2-cyanophenyl)-5-methoxy-2-oxopyridin-1(2H)-yl]-4-methylpentanoic acid

TFA

→

2-[4-(5-Chloro-2-cyanophenyl)-5-methoxy-2-oxopyridin-1(2H)-yl]-4-methylpentanoic acid

Условия реакции

Методика

178 mg (purity 92%, 0.38 mmol) of tert-butyl 2-[4-(5-chloro-2-cyanophenyl)-5-methoxy-2-oxopyridin-1(2H)-yl]-4-methylpentanoic acid (racemate) were hydrolysed with TFA according to General Method 6A. Yield: 165 mg (purity 85%, 98% of theory)

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