Реакция #84038

ord-f4c8c1f0d6204851adc933a395a25692

Уравнение реакции

N[C@H](C(=O)O)C1CCOCC1
(S)-2-amino-2-(tetrahydro-2H-pyran-4-yl)acetic acid
COC(=O)N[C@H](C(=O)O)C(C)C
N-methoxycarbonyl-L-Valine
→
COC(=O)NC(C(=O)O)C1CCOCC1
2-(methoxycarbonylamino)-2-(tetrahydro-2H-pyran-4-yl)acetic acid

Реактанты

N[C@H](C(=O)O)C1CCOCC1
(S)-2-amino-2-(tetrahydro-2H-pyran-4-yl)acetic acid
COC(=O)N[C@H](C(=O)O)C(C)C
N-methoxycarbonyl-L-Valine

Реагенты

Нет

Условия реакции

Подробные условия
See reaction.notes.procedure_details.

Методика

2-(methoxycarbonylamino)-2-(tetrahydro-2H-pyran-4-yl)acetic acid was synthesized similar to N-methoxycarbonyl-L-Valine, using (S)-2-amino-2-(tetrahydro-2H-pyran-4-yl)acetic acid instead of L-Valine.

Источник

DOI: 10.6084/m9.figshare.5104873.v1Патент: US09433609B2uspto-grants-2016_09