Реакция #8162

Уравнение реакции

cyclohexyl hydrazine hydrochloride

2-acetyl-3-oxobutyric acid ethyl ester

pyridine

→

1-cyclohexyl-3,5-dimethyl-1H-pyrazole-4-carboxylic acid ethyl ester

Растворители

ethanol

Условия реакции

Методика

Similar to Example 1, equimolar amounts of cyclohexyl hydrazine hydrochloride and 2-acetyl-3-oxobutyric acid ethyl ester were combined in a solution of 50% pyridine in ethanol. Analysis confirmed synthesis of the named product (m.p. 66° C.–67° C.).

Источник