Реакция #79982

Уравнение реакции

3,3-Dimethylacryloyl chloride

4-bromo-N-methyl-aniline

triethyl amine

→

title product

N-(4-Bromophenyl)-N-methyl-3-methyl-2-butenamide

Растворители

dichloromethane

Условия реакции

Обработка

1. 1
   Промывкаthe reaction mixture was washed with water
2. 2
   Сушкаthe organic phase was dried over anhydrous sodium sulfate
3. 3
   Другоеevaporated in vacuo

Методика

3,3-Dimethylacryloyl chloride (3 mL, 27 mmol) was added to a solution of 4-bromo-N-methyl-aniline (4.55 g, 25 mmol) in 150 mL of dichloromethane followed after 5 minutes by triethyl amine (5 mL, 33 mmol). After 2.5 h at ambient temperature, the reaction mixture was washed with water and the organic phase was dried over anhydrous sodium sulfate and evaporated in vacuo to afford the title product as a brown oil in quantitative yield.

Источник