Реакция #792146

Уравнение реакции

(E)-1-(4-hydroxybenzo[d][1,3]dioxol-5-yl)-3-(pyridin-2-yl)prop-2-en-1-one

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title compound

Выход 59.6%

1-(4-hydroxybenzo[d][1,3]dioxol-5-yl)-3-(pyridin-2-yl)propan-1-one

Выход 59.6%

Растворители

methanol

Условия реакции

Обработка

1. 1
   Другоеto give a yellow solution
2. 2
   ФильтрацияThe reaction mixture was filtered
3. 3
   Другоеevaporated
4. 4
   Промывкаthe solid residue was washed with diethylether
5. 5
   Другоеdried

Методика

(E)-1-(4-hydroxybenzo[d][1,3]dioxol-5-yl)-3-(pyridin-2-yl)prop-2-en-1-one (0.5 g, 1.857 mmol) was added to methanol (50 ml) to give a yellow solution. Palladium on carbon (0.05 g) was added. Product was hydrogenated while stirring till conversion was completed (checked by TLC). The reaction mixture was filtered, evaporated and the solid residue was washed with diethylether, and dried to yield 0.3 g (57%) of the title compound.

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