Реакция #78044

Уравнение реакции

4,4-difluoro-piperidine hydrochloride

Boc-(L)-isoleucine

→

(S)-2-amino-1-(4,4-difluoro-piperidin-1-yl)-3-methyl-pentan-1-one hydrochloride

Условия реакции

Методика

(S)-2-amino-1-(4,4-difluoro-piperidin-1-yl)-3-methyl-pentan-1-one hydrochloride was prepared from 4,4-difluoro-piperidine hydrochloride and Boc-(L)-isoleucine as described in Example 1 (mp 190-192° C.).

Источник