Реакция #77372

ord-89d9f562102c47199e755c20e85166da

Уравнение реакции

O=C1Cc2cc(S(=O)(=O)N3CCc4ccccc43)ccc2N1
5-(2,3-Dihydro-indole-1-sulfonyl)-1,3-dihydro-indol-2-one
O=Cc1cc2cc(OCCN3CCCC3)ccc2[nH]1
5-(2-pyrrolidin-1-yl-ethoxy)-1H-indole-2-carbaldehyde
→
O=C1Nc2ccc(S(=O)(=O)N3CCc4ccccc43)cc2C1=Cc1cc2cc(OCCN3CCCC3)ccc2[nH]1
title compound
O=C1Nc2ccc(S(=O)(=O)N3CCc4ccccc43)cc2C1=Cc1cc2cc(OCCN3CCCC3)ccc2[nH]1
5-(2,3-Dihydro-indole-1-sulfonyl)-3-[5-(2-pyrrolidin-1-yl-ethoxy)-1H-indol-2-ylmethylene]-1,3-dihydro-indol-2-one

Реактанты

O=C1Cc2cc(S(=O)(=O)N3CCc4ccccc43)ccc2N1
5-(2,3-Dihydro-indole-1-sulfonyl)-1,3-dihydro-indol-2-one
O=Cc1cc2cc(OCCN3CCCC3)ccc2[nH]1
5-(2-pyrrolidin-1-yl-ethoxy)-1H-indole-2-carbaldehyde

Реагенты

Нет

Условия реакции

Подробные условия
See reaction.notes.procedure_details.

Методика

5-(2,3-Dihydro-indole-1-sulfonyl)-1,3-dihydro-indol-2-one was condensed with 5-(2-pyrrolidin-1-yl-ethoxy)-1H-indole-2-carbaldehyde to give the title compound.

Источник

DOI: 10.6084/m9.figshare.5104873.v1Патент: US06706709B2uspto-grants-2004_03