Реакция #77146

ord-f5a4a6fb0b6d424faa6f5ec4226d6592

Уравнение реакции

COc1cc(CC2c3cc(OC)c(OC)cc3CCN2CC(=O)NCc2ccccc2)ccc1O
2-[1-(4-hydroxy-3-methoxy-benzyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-N-benzyl-acetamide
O=C(Cl)N1CCOCC1
4-morpholine-carbonyl chloride
→
COc1cc2c(cc1OC)C(Cc1ccc(OC(=O)N3CCOCC3)c(OC)c1)N(CC(=O)NCc1ccccc1)CC2
2-{1-[3-Methoxy-4-(4-morpholine-carbonyloxy)-benzyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl}-N-benzyl-acetamide

Реактанты

COc1cc(CC2c3cc(OC)c(OC)cc3CCN2CC(=O)NCc2ccccc2)ccc1O
2-[1-(4-hydroxy-3-methoxy-benzyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-N-benzyl-acetamide
O=C(Cl)N1CCOCC1
4-morpholine-carbonyl chloride

Реагенты

Нет

Условия реакции

Подробные условия
See reaction.notes.procedure_details.

Методика

prepared by reaction of 2-[1-(4-hydroxy-3-methoxy-benzyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-N-benzyl-acetamide with 4-morpholine-carbonyl chloride

Источник

DOI: 10.6084/m9.figshare.5104873.v1Патент: US06703392B2uspto-grants-2004_03