Реакция #76955

ord-7b3fc30f7e9c43eea6c01ff199498c96

Уравнение реакции

COc1ccc(OC)c(CC2NCCc3c(OC)ccc(OC)c32)c1
1-(2,5-Dimethoxy-benzyl)-5,8-dimethoxy-1,2,3,4-tetrahydroisoquinoline
O=C(Br)CBr
2-bromoacetyl bromide
NC1Cc2ccccc2C1
2-amino-indane
→
COc1ccc(OC)c(CC2c3c(OC)ccc(OC)c3CCN2CC(=O)NC2Cc3ccccc3C2)c1
2-[1-(2,5-Dimethoxy-benzyl)-5,8-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-N-(indan-2-yl)-acetamide

Реактанты

COc1ccc(OC)c(CC2NCCc3c(OC)ccc(OC)c32)c1
1-(2,5-Dimethoxy-benzyl)-5,8-dimethoxy-1,2,3,4-tetrahydroisoquinoline
O=C(Br)CBr
2-bromoacetyl bromide
NC1Cc2ccccc2C1
2-amino-indane

Реагенты

Нет

Условия реакции

Подробные условия
See reaction.notes.procedure_details.

Методика

prepared by reaction of 1-(2,5-Dimethoxy-benzyl)-5,8-dimethoxy-1,2,3,4-tetrahydroisoquinoline and 2-bromoacetyl bromide with 2-amino-indane

Источник

DOI: 10.6084/m9.figshare.5104873.v1Патент: US06703392B2uspto-grants-2004_03