Реакция #75655

Уравнение реакции

3,5-dichloroaniline

ethylglyoxalate

2,5-dimethylstyrene

trifluoroacetic acid

→

Compound 23

Выход 89.0%

5,7-dichloro-4-(2,5-dimethylphenyl)-1,2,3,4-tetrahydroquinoline-2-carboxylic Acid Ethyl Ester

Выход 89.0%

Растворители

acetonitrile

Условия реакции

Методика

Compound 23 was prepared in a yield of 89% by the basic process from 5.0 mmol 3,5-dichloroaniline, 5.5 mmol ethylglyoxalate solution (50% toluene), 15.0 mmol 2,5-dimethylstyrene and 5.0 mmol trifluoroacetic acid in 30.0 ml acetonitrile.

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