Реакция #75643

Уравнение реакции

4-chloroaniline

ethylglyoxalate

3-fluorostyrene

trifluoroacetic acid

→

Compound 7

Выход 66.0%

6-chloro-4-(3-fluorophenyl)-1,2,3,4-tetrahydroquinoline-2-carboxylic Acid Ethyl Ester

Выход 66.0%

Растворители

acetonitrile

Условия реакции

Методика

Compound 7 was prepared in a yield of 66% by the basic process from 5.0 mmol 4-chloroaniline, 5.5 mmol ethylglyoxalate solution (50% toluene), 15.0 mmol 3-fluorostyrene and 5.0 mmol trifluoroacetic acid in 30.0 ml acetonitrile.

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