Реакция #75402

ord-861f45d8930049aebc72cc5caecb3e47

Уравнение реакции

CC1(C)N=CC2=C3N=C(c4ccccc4)N=C3C(=O)CC2C1=O.Cl
7,7-dimethyl-2-phenyl-5H,7H-imidazo(4,5-h]isoquinoline-4,6-dione hydrochloride
CN(C)CCCCl.Cl
3-dimethylamino-propyl chloride hydrochloride
→
CN(C)CCCC1C(=O)C2=NC(c3ccccc3)=NC2=C2C=NC(C)(C)C(=O)C21.Cl.Cl
7,7-Dimethyl-2-phenyl-5-(3-dimethylamino-propyl)-5H,7H-imidazo[4,5-h]isoquinoline-4,6-dione dihydrochloride

Реактанты

CC1(C)N=CC2=C3N=C(c4ccccc4)N=C3C(=O)CC2C1=O.Cl
7,7-dimethyl-2-phenyl-5H,7H-imidazo(4,5-h]isoquinoline-4,6-dione hydrochloride
CN(C)CCCCl.Cl
3-dimethylamino-propyl chloride hydrochloride

Реагенты

Нет

Условия реакции

Подробные условия
See reaction.notes.procedure_details.

Методика

Prepared analogous to Example 23 from 3.4 gm of 7,7-dimethyl-2-phenyl-5H,7H-imidazo(4,5-h]isoquinoline-4,6-dione hydrochloride and 1.7gm of 3-dimethylamino-propyl chloride hydrochloride (reaction temperature: 50°-60° C.; reaction time: 18 hous).

Источник

DOI: 10.6084/m9.figshare.5104873.v1Патент: US04176184uspto-grants-1979_11