Реакция #75213

ord-2476db3253c646b6b5b3b55f6f07319c

Уравнение реакции

N[C@@H](CC1(C(=O)C(CS)CS)C=CC=CC1)C(=O)O
1-[2-(mercaptomethyl)-3-mercaptopropanoyl]-L-phenylalanine
N[C@@H](Cc1ccccc1)C(=O)O
L-phenylalanine
O=C(O)[C@@H]1CCCN1
L-proline
N[C@@H](Cc1ccccc1)C(=O)O
L-phenylalanine
→
O=C(N[C@@H](Cc1ccccc1)C(=O)O)C(CS)CS
N-[2-(Mercaptomethyl)-3-mercaptopropanoyl]-L-phenylalanine

Реактанты

N[C@@H](CC1(C(=O)C(CS)CS)C=CC=CC1)C(=O)O
1-[2-(mercaptomethyl)-3-mercaptopropanoyl]-L-phenylalanine
N[C@@H](Cc1ccccc1)C(=O)O
L-phenylalanine
O=C(O)[C@@H]1CCCN1
L-proline
N[C@@H](Cc1ccccc1)C(=O)O
L-phenylalanine

Реагенты

Нет

Условия реакции

Подробные условия
See reaction.notes.procedure_details.

Обработка

  1. 1
    Другоеare obtained

Методика

By substituting L-phenylalanine for the L-proline in the procedure of Example 3B, and then submitting the product to the procedure of Example 4, 1-[2-acetylthiomethyl)-3-acetylthiopropanoyl]-L-phenylalanine and 1-[2-(mercaptomethyl)-3-mercaptopropanoyl]-L-phenylalanine are obtained.

Источник

DOI: 10.6084/m9.figshare.5104873.v1Патент: US04175199uspto-grants-1979_11