Реакция #75211

ord-fa25e4d19e084aefa77772d669d312ea

Уравнение реакции

COC(C)C(SC(=O)c1ccccc1)C(=O)N1CCC[C@H]1C(=O)O
1-[2-benzoylthio-3-methoxybutanoyl]-L-proline
CSCC(CSC(C)=O)C(=O)N1CCC[C@H]1C(=O)O
1-[3-acetylthio-2-(methylthiomethyl)propanoyl]-L-proline
→
COC(C)C(S)C(=O)N1CCC[C@H]1C(=O)O
1-[2-mercapto-3-methoxybutanoyl]-L-proline

Реактанты

COC(C)C(SC(=O)c1ccccc1)C(=O)N1CCC[C@H]1C(=O)O
1-[2-benzoylthio-3-methoxybutanoyl]-L-proline
CSCC(CSC(C)=O)C(=O)N1CCC[C@H]1C(=O)O
1-[3-acetylthio-2-(methylthiomethyl)propanoyl]-L-proline

Реагенты

Нет

Условия реакции

Подробные условия
See reaction.notes.procedure_details.

Методика

By substituting 1-[2-benzoylthio-3-methoxybutanoyl]-L-proline for the 1-[3-acetylthio-2-(methylthiomethyl)propanoyl]-L-proline in the procedure of Example 17, 1-[2-mercapto-3-methoxybutanoyl]-L-proline is obtained.

Источник

DOI: 10.6084/m9.figshare.5104873.v1Патент: US04175199uspto-grants-1979_11