Реакция #75200

Уравнение реакции

(2-Acetylthiomethyl-3-(acetylthio)propanoyl]-L-proline

hydrochloric acid

→

1-(2-Mercaptomethyl-3-mercaptopropanoyl)-L-proline

Растворители

water

ammonia

Условия реакции

Обработка

1. 1
   workup.WAITAfter twenty minutes
2. 2
   ФильтрацияThe crystalline precipitate 1-(2-mercaptomethyl-3-mercaptopropanoyl)-L-proline is filtered
3. 3
   Другоеdried

Методика

1-[(2-Acetylthiomethyl-3-(acetylthio)propanoyl]-L-proline (1.2 g.) is dissolved in a mixture of water (12 ml.) and concentrated ammonia (12 ml.) under an atmosphere of argon. After twenty minutes, the mixture is acidified with concentrated hydrochloric acid. The crystalline precipitate 1-(2-mercaptomethyl-3-mercaptopropanoyl)-L-proline is filtered and dried, yield 0.63 g., m.p. 138°-140°.

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