Реакция #743435

Уравнение реакции

(1S,2R,4S)-7-oxabicyclo[2.2.1]-hept-5-ene-2-carboxylic acid

→

title compound

(1S,2R,4S)-7-Oxabicyclo[2.2.1]heptane-2-carboxylic acid

Растворители

ethanol

Условия реакции

Обработка

1. 1
   ФильтрацияThe reaction mixture is clarified by filtration
2. 2
   Другоеthe filtrate is evaporated

Методика

A solution of 1 mmol of (1S,2R,4S)-7-oxabicyclo[2.2.1]-hept-5-ene-2-carboxylic acid [185840-15-7] in 30 ml of ethanol is hydrogenated in the presence of 0.150 g of Pd/C 10% at room temperature until conversion is complete. The reaction mixture is clarified by filtration, and the filtrate is evaporated. The title compound is obtained from the residue by flash chromatography (SiO2 60 F).

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