Реакция #73082

Уравнение реакции

Intermediate A

(R)-Methyl 2-((2-chloro-5-nitropyrimidin-4-yl)(cyclopentyl)amino)butanoate

→

(R)-methyl 2-((2-chloro-5-nitropyrimidin-4-yl)(isopropyl)amino)butanoate

Растворители

acetone

Условия реакции

Обработка

1. 1
   ДругоеIntermediate C-1 was prepared similarly to the synthetic methods

Методика

Intermediate C-1 was prepared similarly to the synthetic methods used to prepare Intermediate A with the exception that acetone was used instead of cyclopentanone in the reductive amination step.

Источник