Реакция #723177

ord-9e5f3ebd0d7a49dc84cccf4b3de18ec9

Уравнение реакции

COc1cccc(OC)c1OC
pyrogallol trimethyl ether
O=S(=O)(O)Cl
chlorosulfonic acid
→
COc1ccc(S(=O)(=O)Cl)c(OC)c1OC
2,3,4-Trimethoxybenzenesulfonyl chloride

Реактанты

COc1cccc(OC)c1OC
pyrogallol trimethyl ether
O=S(=O)(O)Cl
chlorosulfonic acid

Реагенты

Нет

Растворители

ClC(Cl)Cl
chloroform

Условия реакции

Подробные условия
See reaction.notes.procedure_details.

Методика

2,3,4-Trimethoxybenzenesulfonyl chloride is synthesized by reaction of pyrogallol trimethyl ether with chlorosulfonic acid in chloroform at 0° C. according to the procedure described in G. Pifferi and R. Monguzzi, Journal of Pharmaceutical Sciences, 1973, 62, 1393.

Источник

DOI: 10.6084/m9.figshare.5104873.v1Патент: US06191170B1uspto-grants-2001_02