Реакция #70835

Уравнение реакции

6-chloronicotinic acid

SOCl2

→

desired product

Выход 93.0%

6-Chloronicotinoyl chloride hydrochloride

Выход 93.0%

Условия реакции

Обработка

1. 1
   Температураto reflux for 2 h
2. 2
   ДругоеThe SOCl2 was evaporated to dryness

Методика

A solution of 6-chloronicotinic acid (10.00 g, 63.5 mmol) in SOCl2 (37 mL) was heated to reflux for 2 h. The SOCl2 was evaporated to dryness, to afford 12.56 g of the desired product (yield: 93%).

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