Реакция #696695

Уравнение реакции

1,4-diaminobutane

triethylamine

2-chloro-2-methyl-3-nitrosopentane

→

2-(4-aminobutyl)amino-2-methyl-3-pentanone oxime

Растворители

acetonitrile

acetonitrile

Условия реакции

Обработка

1. 1
   Другоеto precipitate
2. 2
   workup.STIRRINGThe reaction mixture was stirred overnight
3. 3
   Фильтрацияthe product was filtered off
4. 4
   Другоеdried in vacuo
5. 5
   Другоеto give a white powder, (0.5 g; 86%)

Методика

To a stirred solution of 1,4-diaminobutane (0.26 g; 2.9 mmol) and triethylamine (0.33 g; 3.2 mmol) in acetonitrile (5 ml) was added a solution of 2-chloro-2-methyl-3-nitrosopentane (0.485 g; 3.24 mmol) in acetonitrile (5 ml). After stirring for ca 10 minutes the product began to precipitate. The reaction mixture was stirred overnight and the product was filtered off and dried in vacuo to give a white powder, (0.5 g; 86%).

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