Реакция #696692

Уравнение реакции

carbon dioxide

oleic acid

aminoguanidine bicarbonate

toluene

→

Aminoguanidine Oleamide

Растворители

water

Условия реакции

Обработка

1. 1
   ТемператураThe reaction mixture was heated
2. 2
   Температураto reflux under a nitrogen blanket
3. 3
   ДругоеA total of about 57 ml of water was collected from the reaction by means of a Dean-Stark trap
4. 4
   Другоеthe removal of toluene
5. 5
   Фильтрацияwas filtered

Методика

A 5 liter, 3-neck flask was charged with 847.5 grams (3 moles) oleic acid, 3 moles of aminoguanidine bicarbonate, 300 mls of toluene and 15 drops of a silicone anti-foam agent. The reaction mixture was heated to reflux under a nitrogen blanket. Vigorous foaming was noted as carbon dioxide gas evolved. When the foaming subsided, water evolution began. A total of about 57 ml of water was collected from the reaction by means of a Dean-Stark trap. The temperature of the reaction mixture was raised to about 140° C. to facilitate the removal of toluene. The reaction product, believed to be primarily aminoguanidine oleamide, was filtered and placed under nitrogen for storage.

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