Реакция #6858

Уравнение реакции

Benzyl chloroformate

6-methoxy-1-methyl-3,4-dihydroisoquinoline

triethylamine

→

6-methoxy-1-methylene-3,4-dihydro-1H-isoquinoline-2-carboxylic acid benzyl ester

Растворители

dichloromethane

Условия реакции

Обработка

1. 1
   Другоеthe volatile material was evaporated

Методика

Benzyl chloroformate (0.30 mL) was added to an ice-cold solution of 6-methoxy-1-methyl-3,4-dihydroisoquinoline (0.36 g) and triethylamine (0.58 mL) in 10 mL dichloromethane. After 0.5 h, the volatile material was evaporated to furnish 0.66 g of 6-methoxy-1-methylene-3,4-dihydro-1H-isoquinoline-2-carboxylic acid benzyl ester.

Источник