Реакция #674287

ord-9fb1ff1cb2d94f1da5086a474289cc48

Уравнение реакции

[Ca+2].[Cl-].[Cl-]
calcium chloride
O=P([O-])([O-])O
hydrogen phosphate
[Na+].[OH-]
NaOH
→
O=P([O-])([O-])[O-].O=P([O-])([O-])[O-].[Ca+2].[Ca+2].[Ca+2]
Calcium Phosphate

Реактанты

[Ca+2].[Cl-].[Cl-]
calcium chloride
O=P([O-])([O-])O
hydrogen phosphate
[Na+].[OH-]
NaOH

Реагенты

Нет

Растворители

O=P([O-])([O-])[O-]
phosphate

Условия реакции

Подробные условия
See reaction.notes.procedure_details.

Обработка

  1. 1
    ДругоеCaP NPs
  2. 2
    Другоеwere obtained by filtration of the suspension through a 0.22 μm
  3. 3
    Фильтрацияfilter
  4. 4
    ДругоеCaP NPs
  5. 5
    Другоеwere stored at 4° C. before use
  6. 6
    ДругоеCaP/ZOL-NPs complexes (CaPZ NPs) were prepared

Методика

An aqueous solution of calcium chloride (18 mM) was added, dropwise and under magnetic stirring, to an aqueous solution on dibasic hydrogen phosphate (10.8 mM). The pH of both solutions was adjusted beforehand to 9.5 with NaOH. CaP NPs were obtained by filtration of the suspension through a 0.22 μm filter. CaP NPs were stored at 4° C. before use. CaP/ZOL-NPs complexes (CaPZ NPs) were prepared by mixing a CaP NPs dispersion with an aqueous solution of (50 mg/ml of ZOL in phosphate buffer at pH 9.5), at a volume ratio of 50:1.

Источник

DOI: 10.6084/m9.figshare.5104873.v1Патент: US09226897B2uspto-grants-2016_01