Реакция #66808

Уравнение реакции

ethyl 4-chloro-5,7-dihydro-6H-pyrrolo[3′,4′:4,5]thieno[2,3-d]pyrimidine-6-carboxylate

Ethyl 4-chloro-5,7-dihydro-6H-pyrrolo[3′,4′:4,5]thieno[2,3-d]pyrimidine-6-carboxylate

1-(3-fluorobenzyl)-1H-indazol-5-amine

1-(3-Fluorobenzyl)-1H-indazol-5-amine

→

title compound

Ethyl 4-{[1-(3-fluorobenzyl)-1H-indazol-5-yl]amino}-5,7-dihydro-6H-pyrrolo[3′,4′:4,5]thieno[2,3-d]pyrimidine-6-carboxylate

Условия реакции

Методика

In analogy to Example 22A, ethyl 4-chloro-5,7-dihydro-6H-pyrrolo[3′,4′:4,5]thieno[2,3-d]pyrimidine-6-carboxylate from Example 21A (100 mg, 0.35 mmol) and 1-(3-fluorobenzyl)-1H-indazol-5-amine from Example 8A (89 mg, 0.37 mmol) were reacted to the title compound to yield 120 mg (68%).

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