Реакция #66284

ord-41f03660fd3e4b6c87011af3b87c8562

Уравнение реакции

CC1(C)OB(c2ccc(C(=O)O)cc2)OC1(C)C
4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid
O[C@H]1CNC[C@@H]1O
(3S,4S)-pyrrolidine-3,4-diol
→
CC1(C)OB(c2ccc(C(=O)N3C[C@H](O)[C@@H](O)C3)cc2)OC1(C)C
title compound
CC1(C)OB(c2ccc(C(=O)N3C[C@H](O)[C@@H](O)C3)cc2)OC1(C)C
((3S,4S)-3,4-dihydroxypyrrolidin-1-yl)(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanone

Реактанты

CC1(C)OB(c2ccc(C(=O)O)cc2)OC1(C)C
4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid
O[C@H]1CNC[C@@H]1O
(3S,4S)-pyrrolidine-3,4-diol

Реагенты

Нет

Условия реакции

Подробные условия
See reaction.notes.procedure_details.

Методика

The title compound was prepared by the procedure as described in Example 101 (Step H) using 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid and (3S,4S)-pyrrolidine-3,4-diol.

Источник

DOI: 10.6084/m9.figshare.5104873.v1Патент: US08524702B2uspto-grants-2013_09