Реакция #65102

Уравнение реакции

aluminium chloride

terphenyl

acetyl chloride

→

4-acetyl-p-terphenyl

Выход 119.0%

Растворители

benzene

Условия реакции

Обработка

1. 1
   Другоеsubjected to reaction at -5° C. for 1 hour and further at 10° C. for 1 hour
2. 2
   ДругоеThe solid materials thus formed
3. 3
   Другоеwere separated by filtration
4. 4
   Промывкаwashed with a total of 4 liter of methanol in few instalments
5. 5
   Другоеrecrystallized from chloroform

Методика

After a mixture of 172 g of terphenyl, 860 ml of benzene, and 353 g of acetyl chloride was cooled to -5° C., it was added with a total of 200 g of anhydrous aluminium chloride in few instalments, and subjected to reaction at -5° C. for 1 hour and further at 10° C. for 1 hour. The solid materials thus formed were separated by filtration, washed with a total of 4 liter of methanol in few instalments, and then recrystallized from chloroform to obtain 121 g of 4-acetyl-p-terphenyl, 2. The yield was 59%.

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