Реакция #65060

Уравнение реакции

Sodium cyanide

4-chlorobenzenediazonium tetrafluoroborate

→

4-Chlorobenzonitrile

Выход 75.0%

Растворители

water

water

Условия реакции

Обработка

1. 1
   workup.STIRRINGstirred until it
2. 2
   Другоеto react at room temperature
3. 3
   ЭкстракцияThe mixture was extracted by ethyl acetate
4. 4
   Другоеhad been formed in 75% yield

Методика

Sodium cyanide (2.94 g; 0.06 mol) was added to water and stirred. Cuprous cyanide (2.7 g; 0.03 mol) was added to the mixture stirred until it became homogeneous. 4-chlorobenzenediazonium tetrafluoroborate (5.66 g; 0.025 mol) in water (10 ml) was added to one portion. The mixture was allowed to react at room temperature. The mixture was extracted by ethyl acetate and the extract analysed by means of gas chromatography which indicated that 4-chlorobenzonitrile had been formed in 75% yield.

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