Реакция #64980

Уравнение реакции

5-methyl-1,4-dihydropyridine-2,3dicarboxylic acid N-benzylimide

charcoal

→

5-Methyl-hexahydropyridine-2,3-dicarboxylic acid N-benzylimide

Растворители

tetrahydrofuran

Условия реакции

Обработка

1. 1
   ФильтрацияThen the catalyst is filtered off
2. 2
   Концентрированиеthe filtrate is concentrated by evaporation

Методика

17.5 g (70 mmol) of 5-methyl-1,4-dihydropyridine-2,3dicarboxylic acid N-benzylimide are hydrogenated in 150 ml of tetrahydrofuran at 70° C. and under 100 bar over palladium on active charcoal. Then the catalyst is filtered off and the filtrate is concentrated by evaporation. The solid oily residue (13.0 g) is used as a crude product in the next stage.

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