Реакция #64859

Уравнение реакции

trans-1,4-dibromo-2-butene

potassium phthalimide

→

title product

TRANS-1-BROMO-4-PHTHALIMIDO-2-BUTENE

Растворители

dimethyl formamide

Условия реакции

Обработка

1. 1
   КонцентрированиеThen the reaction mixture was concentrated in vacuo
2. 2
   workup.DISSOLUTIONdissolved in ethyl acetate
3. 3
   Промывкаwashed with brine

Методика

A mixture of trans-1,4-dibromo-2-butene (6.4 g, 30 mmol) and potassium phthalimide (5.6 g, 30 mmol) in anhydrous dimethyl formamide (200 ml) was heated at 50° C. for 24 h. Then the reaction mixture was concentrated in vacuo, dissolved in ethyl acetate, washed with brine and the pure title product was obtained by flash chromatography on silica gel (ethyl acetate: hexane; 15:85) (3.2 g, 40%).

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