Реакция #64673

Уравнение реакции

1-Chloro-4-hydroxythioxanthone

potassium carbonate

n-Propyl bromide

→

title compound

Выход 75.5%

1-Chloro-4-n-propoxythioxanthone

Выход 75.5%

Растворители

acetone

Условия реакции

Обработка

1. 1
   Температураthe resulting mixture heated
2. 2
   Температураunder reflux for 16 hours
3. 3
   ТемператураThe mixture was then cooled
4. 4
   Другоеquenched on to water (250 ml)
5. 5
   ФильтрацияThe solid was filtered
6. 6
   Промывкаwashed with water the resulting damp solid
7. 7
   Другоеrecrystallised from ethanol (50 ml)

Методика

1-Chloro-4-hydroxythioxanthone (7.8 g; 0.03 mol) prepared as above and potassium carbonate (5.0 g; 0.036 mol) was stirred and refluxed for 10 minutes in acetone (50 ml). n-Propyl bromide (5.5 g; 0.045 mol) was added and the resulting mixture heated under reflux for 16 hours. The mixture was then cooled and quenched on to water (250 ml). The solid was filtered and washed with water the resulting damp solid recrystallised from ethanol (50 ml) to afford the title compound (6.9 g; 75.5%) of mp 102°-3°. Analysis C16H13ClO2S=304.777 Requires C 63.05%; H 4.30%; Cl 11.63%; S 10.52% Found C 63.14%; H 4.37%; Cl 11.66%; S 10.63%

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