Реакция #644569

Уравнение реакции

allyl bromide

potassium carbonate

potassium iodide

2-hydroxyacetophenone

→

title compound

1-[2-(Allyloxy)phenyl]ethanone

Растворители

acetone

Условия реакции

Обработка

1. 1
   Фильтрацияis followed by filtration and removal of the solvent in vacuo
2. 2
   workup.DISSOLUTIONThe residue is dissolved in toluene
3. 3
   Промывкаwashed with 10% strength sodium hydroxide solution and water
4. 4
   КонцентрированиеConcentration

Методика

542 g (3.9 mol) of 2-hydroxyacetophenone are heated to reflux with 592 g (4.9 mol) of allyl bromide, 1000 g (7.2 mol) of potassium carbonate and 13.2 g (79 mmol) of potassium iodide in 2.4 liters of acetone for 24 h. Cooling to room temperature is followed by filtration and removal of the solvent in vacuo. The residue is dissolved in toluene and washed with 10% strength sodium hydroxide solution and water. Concentration results in 689 g (98% of theory) of the title compound.

Источник