Реакция #64356

Уравнение реакции

N-methyl-6-nitro-2,2-dimethyl-2H-1-benzopyran-4-carboxamide

ethyl iodide

hydride

tetrahydrofuran

Dichloromethane

→

N-ethyl-N-methyl-6-nitro-2,2-dimethyl-2H-1-benzopyran-4-carboxamide

Условия реакции

Обработка

1. 1
   Температураwas heated
2. 2
   Температураat reflux for 30 minutes
3. 3
   Другоеany insoluble matter was removed by filtration
4. 4
   ДругоеThe filtrate was recrystallized from a mixture of diethyl ether and n-hexane

Методика

A mixture of 0.53 g of N-methyl-6-nitro-2,2-dimethyl-2H-1-benzopyran-4-carboxamide, 1.60 g of ethyl iodide, 0.09 g of sodlum hydride, and 10 ml of tetrahydrofuran was heated at reflux for 30 minutes. Dichloromethane was added to the reaction mixture, and any insoluble matter was removed by filtration. The filtrate was recrystallized from a mixture of diethyl ether and n-hexane to obtain 0.45 g of N-ethyl-N-methyl-6-nitro-2,2-dimethyl-2H-1-benzopyran-4-carboxamide represented by formula shown below.

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