Реакция #6432

Уравнение реакции

sodium azide

oxaphosphorinane

2-phenoxy-2-oxo-6-iodomethyl-1,2-oxaphosphorinane

→

2-phenoxy-2-oxo-6-(azidomethyl)-1,2-oxaphosphorinane

Выход 96.0%

Растворители

benzene DMF

Условия реакции

Методика

A suspension containing two equivalents of sodium azide, one equivalent of the above-prepared iodonated oxaphosphorinane and a catalytic amount of about 0.1 equivalent of tetrabutylammonium bromide in benzene/DMF (1:1) was heated to 60-80 degrees C. for 16 hours to produce 2-phenoxy-2-oxo-6-(azidomethyl)-1,2-oxaphosphorinane in 96 percent yield as a white solid.

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