Реакция #64113

Уравнение реакции

POCl3

4-hydroxyquinazoline

1,2,4-triazole

→

Quinazoline

Растворители

pyridine

Условия реакции

Методика

Intermediates of formula (3) wherein L is 1,2,4-triazol-1-yl, can be prepared, for example, by adding POCl3 dropwise to a mixture of a 4-hydroxyquinazoline (1 equiv.) of formula (9) and 1,2,4-triazole (3 equiv.) in pyridine at room temperature.

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