Реакция #640589

Уравнение реакции

cyanogen bromide

(±)-trans-1,2-cyclohexanediamine

3,4-difluorobenzaldehyde

→

title compound

(±)-trans-1,3-Bis-(3,4-difluoro-benzyl)octahydro-benzoimidazol-2-ylideneamine

Условия реакции

Обработка

1. 1
   Другоеthe reaction mixture was evaporated to dryness
2. 2
   Промывкаthe crude product washed with ether
3. 3
   Другоеrecrystallized from MeOH

Методика

The title compound was prepared from (±)-trans-1,2-cyclohexanediamine and 3,4-difluorobenzaldehyde by Procedure C. After reacting with cyanogen bromide, the reaction mixture was evaporated to dryness and the crude product washed with ether and recrystallized from MeOH to give the title compound as the hydrogen bromide salt (mp 238-240° C.). MS (ES+) m/z 392 ([M+1]+, 100).

Источник