Реакция #62610

Уравнение реакции

ε(4-nitro 2-methoxy-benzenesulfonamido) caproic acid

charcoal

→

ε(4-amino 2-methoxy-benzenesulfonamido) caproic acid

Выход 98.0%

Растворители

ethyl acetate

Условия реакции

Обработка

1. 1
   Другоеthe hydrogen absorption
2. 2
   Другоеbeing terminated
3. 3
   Фильтрацияthe catalyst is filtered
4. 4
   Концентрированиеthe filtrate concentrated under reduced pressure

Методика

A solution of ε(4-nitro 2-methoxy-benzenesulfonamido) caproic acid (1.4 g) in solution in ethyl acetate (150 cm3) is stirred magnetically under a hydrogen atmosphere in the presence of 5% palladized charcoal (120 mg). After four hours, the hydrogen absorption being terminated, the catalyst is filtered and the filtrate concentrated under reduced pressure. Pure ε(4-amino 2-methoxy-benzenesulfonamido) caproic acid is obtained, with a yield of 98%.

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