Реакция #62392

Уравнение реакции

N′-benzyloxycarbonyl-N-methyl-hydrazine carboxylic acid tert-butyl ester

hydrogen chloride-ethyl acetate

→

title compound

N′-Methyl-hydrazine carboxylic acid benzyl ester hydrochloride

Растворители

ethyl acetate

Условия реакции

Обработка

1. 1
   ДругоеThe solvent was evaporated
2. 2
   Промывкаthe resulting crystals were washed with diethyl ether
3. 3
   Фильтрацияfiltered

Методика

17.7 g of N′-benzyloxycarbonyl-N-methyl-hydrazine carboxylic acid tert-butyl ester was dissolved in 20 mL of ethyl acetate, added with 70 mL 4N hydrogen chloride-ethyl acetate solution, and stirred at room temperature for 4 hours. The solvent was evaporated, and the resulting crystals were washed with diethyl ether and filtered, to afford 11.4 g of the title compound as white crystals.

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