Реакция #619128

ord-230c1f4d0a0347e1ab119c51cfaabd55

Уравнение реакции

N#CSc1cnc(NC(=O)N(C2CCCCC2)C2CCCCC2)s1
1,1-dicyclohexyl-3-(5-thiocyanato-thiazol-2-yl)-urea
OC[C@@H](S)[C@@H](S)CO
dithio-erythritol
ClCCN1CCCC1
1-(2-chloroethyl)-pyrrolidine
→
O=C(Nc1ncc(SCCN2CCCC2)s1)N(C1CCCCC1)C1CCCCC1
1,1-Dicyclohexyl-3-[5-(2-pyrrolidin-1-yl-ethylsulfanyl)-thiazol-2-yl]-urea

Реактанты

N#CSc1cnc(NC(=O)N(C2CCCCC2)C2CCCCC2)s1
1,1-dicyclohexyl-3-(5-thiocyanato-thiazol-2-yl)-urea
OC[C@@H](S)[C@@H](S)CO
dithio-erythritol
ClCCN1CCCC1
1-(2-chloroethyl)-pyrrolidine

Реагенты

Нет

Условия реакции

Подробные условия
See reaction.notes.procedure_details.

Обработка

  1. 1
    ДругоеPrepared

Методика

Prepared as described in general procedure (H) using 1,1-dicyclohexyl-3-(5-thiocyanato-thiazol-2-yl)-urea, dithio-erythritol and 1-(2-chloroethyl)-pyrrolidine

Источник

DOI: 10.6084/m9.figshare.5104873.v1Патент: USRE045183E1uspto-grants-2014_10