Реакция #61658

Уравнение реакции

methyl 3-(2-acetyl-4-benzyloxy-6-nitro-phenyl)-acrylate

→

5-acetyl-7-benzyloxy-3,4-dihydro-1H-quinolin-2-one

Растворители

ethanol

Условия реакции

Обработка

1. 1
   ДругоеThe catalyst is separated off
2. 2
   ДругоеThe product that crystallises out is suction
3. 3
   Фильтрацияfiltered
4. 4
   Другоеdried

Методика

5.0 g (14.07 mmol) methyl 3-(2-acetyl-4-benzyloxy-6-nitro-phenyl)-acrylate are combined with 100 mL ethanol and hydrogenated at 4 bar with Raney nickel as catalyst. The catalyst is separated off and the filtrate is acidified with 15 mL 2 N hydrochloric acid. The product that crystallises out is suction filtered and dried.

Источник