Реакция #61221

Уравнение реакции

N-(4-cyano-2-iodo-5-trifluoromethyl-phenyl)-methanesulfonamide

1-ethylsulfanyl-2-methyl-but-3-yn-2-ol

→

title compound

2-(2-Ethylsulfanyl-1-hydroxy-1-methyl-ethyl)-1-methanesulfonyl-6-trifluoromethyl-1H-indole-5-carbonitrile

Условия реакции

Обработка

1. 1
   ДругоеThis compound was prepared

Методика

This compound was prepared using the general Sonagashira procedure as describe in General Procedures Example C, reacting N-(4-cyano-2-iodo-5-trifluoromethyl-phenyl)-methanesulfonamide (1.0 g, 2.56 mmol) and 1-ethylsulfanyl-2-methyl-but-3-yn-2-ol (0.37 g, 2.56 mmol) to yield the title compound as a yellow sticky oil.

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