Реакция #61032

Уравнение реакции

4-(4-Cyano-2,3-difluoro-phenyl)-piperazine-1-carboxylic acid tert-butyl ester

trifluoroacetic acid

→

title compound

2,3-Difluoro-4-piperazin-1-yl-benzonitrile trifluoro-acetic acid

Растворители

dichloromethane

Условия реакции

Обработка

1. 1
   КонцентрированиеAfter such time the reaction mixture was concentrated in vacuo

Методика

To a solution of 4-(4-Cyano-2,3-difluoro-phenyl)-piperazine-1-carboxylic acid tert-butyl ester (0.72 g) in dichloromethane (5 mL) was added trifluoroacetic acid and the reaction mixture was stirred at room temperature for 30 minutes. After such time the reaction mixture was concentrated in vacuo to yield the title compound (0.63 g). MS (m/e): 224.3 (M+H+, 100%).

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