Реакция #60987

ord-e6c21f315e2e4ac7b1e762d84458329a

Уравнение реакции

CS(=O)(=O)c1ccc(N2CCNCC2)cc1
1-(4-Methanesulfonyl-phenyl)-piperazine
O=C(Cl)c1cc([N+](=O)[O-])ccc1N1CCOCC1
2-Morpholin-4-yl-5-nitro-benzoyl chloride
→
CS(=O)(=O)c1ccc(N2CCN(C(=O)c3cc([N+](=O)[O-])ccc3N3CCOCC3)CC2)cc1
title compound
CS(=O)(=O)c1ccc(N2CCN(C(=O)c3cc([N+](=O)[O-])ccc3N3CCOCC3)CC2)cc1
[4-(4-Methanesulfonyl-phenyl)-piperazin-1-yl]-(2-morpholin-4-yl-5-nitro-phenyl)-methanone

Реактанты

CS(=O)(=O)c1ccc(N2CCNCC2)cc1
1-(4-Methanesulfonyl-phenyl)-piperazine
O=C(Cl)c1cc([N+](=O)[O-])ccc1N1CCOCC1
2-Morpholin-4-yl-5-nitro-benzoyl chloride

Реагенты

Нет

Условия реакции

Подробные условия
See reaction.notes.procedure_details.

Методика

The title compound was prepared according to the procedure described for example 46 from 1-(4-Methanesulfonyl-phenyl)-piperazine and 2-Morpholin-4-yl-5-nitro-benzoyl chloride (76%, yellow solid, MS (m/e): 475.1 (M+H, 100%)

Источник

DOI: 10.6084/m9.figshare.5104873.v1Патент: US07427612B2uspto-grants-2008_09