Реакция #60337

ord-34abbd6512c14bdc9cce57576de710cc

Уравнение реакции

O=Cc1cccc2c1CCC2NC(=O)CC(NS(=O)(=O)c1ccc2ccccc2c1)c1ccccc1
N-(4-formyl-indan-1-yl)-3-(naphthalen-2-yl-sulfonylamino)-3-phenyl-propionamide
C1CCNCC1
piperidine
→
O=C(CC(NS(=O)(=O)c1ccc2ccccc2c1)c1ccccc1)NC1CCc2c(CN3CCCCC3)cccc21
3-(Naphthalen-2-yl-sulfonylamino)-3-phenyl-N-(4-piperidin-1-ylmethyl-indan-1-yl)-propionamide

Реактанты

O=Cc1cccc2c1CCC2NC(=O)CC(NS(=O)(=O)c1ccc2ccccc2c1)c1ccccc1
N-(4-formyl-indan-1-yl)-3-(naphthalen-2-yl-sulfonylamino)-3-phenyl-propionamide
C1CCNCC1
piperidine

Реагенты

Нет

Условия реакции

Подробные условия
See reaction.notes.procedure_details.

Обработка

  1. 1
    Другоеyielding a white solid

Методика

3-(Naphthalen-2-yl-sulfonylamino)-3-phenyl-N-(4-piperidin-1-ylmethyl-indan-1-yl)-propionamide was prepared from N-(4-formyl-indan-1-yl)-3-(naphthalen-2-yl-sulfonylamino)-3-phenyl-propionamide Example 4, Step G and piperidine, using essentially the same procedure described in Example 1, Step H, yielding a white solid. MS (ESI) m/z 568 (M+H)+.

Источник

DOI: 10.6084/m9.figshare.5104873.v1Патент: US07425631B2uspto-grants-2008_09