Реакция #6024

Уравнение реакции

methyl 4-hydroxy-3-propenylbenzoate

potassium carbonate

allyl bromide

→

title compound

Выход 87.0%

methyl 3-(2-propen-1-yl)-4-(2-propen-1-yloxy)benzoate

Выход 87.0%

Растворители

acetone

Условия реакции

Обработка

1. 1
   ФильтрацияThe mixture was filtered through Celite
2. 2
   Промывкаthe filter cake was washed with more acetone and dichloromethane
3. 3
   ДругоеAfter removing the solvents
4. 4
   workup.DISTILLATIONthe resulting oil was distilled under high vacuum

Методика

A solution of 3.04 g (15.8 mmol) of methyl 4-hydroxy-3-propenylbenzoate (Example 42, Step B) was refluxed with anhydrous potassium carbonate (4.37 g, 2 equiv) and allyl bromide (3.5 mL, 2.5 equiv) in acetone overnight. The mixture was filtered through Celite and the filter cake was washed with more acetone and dichloromethane. After removing the solvents, the resulting oil was distilled under high vacuum to give 3.2 g (87%) of the title compound.

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